| Aromatic diamidines as antiparasitic agents MNC Soeiro, EM De Souza, CE Stephens, DW Boykin Expert opinion on investigational drugs 14 (8), 957-972, 2005 | 129 | 2005 |
| Host and parasite apoptosis following Trypanosoma cruzi infection in in vitro and in vivo models EM De Souza, TC Araujo-Jorge, C Bailly, A Lansiaux, MM Batista, ... Cell and tissue research 314 (2), 223-235, 2003 | 99 | 2003 |
| In Vitro and In Vivo Studies of the Antiparasitic Activity of Sterol 14α-Demethylase (CYP51) Inhibitor VNI against Drug-Resistant Strains of Trypanosoma cruzi MNC Soeiro, EM de Souza, CF da Silva, DGJ Batista, MM Batista, ... Antimicrobial Agents and Chemotherapy 57 (9), 4151-4163, 2013 | 86 | 2013 |
| Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis EM De Souza, A Lansiaux, C Bailly, WD Wilson, Q Hu, DW Boykin, ... Biochemical Pharmacology 68 (4), 593-600, 2004 | 86 | 2004 |
| Pharmacological inhibition of transforming growth factor β signaling decreases infection and prevents heart damage in acute chagas' Disease MC Waghabi, EM de Souza, GM de Oliveira, M Keramidas, JJ Feige, ... Antimicrobial agents and chemotherapy 53 (11), 4694-4701, 2009 | 78 | 2009 |
| Activity of “reversed” diamidines against Trypanosoma cruzi “in vitro” CF Silva, MM Batista, RA Mota, EM de Souza, CE Stephens, P Som, ... Biochemical Pharmacology 73 (12), 1939-1946, 2007 | 75 | 2007 |
| In Vitro and In Vivo Studies of the Trypanocidal Activity of a Diarylthiophene Diamidine against Trypanosoma cruzi CF da Silva, MM Batista, DGJ Batista, EM de Souza, PB da Silva, ... Antimicrobial Agents and Chemotherapy 52 (9), 3307-3314, 2008 | 73 | 2008 |
| Oral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease FL de Oliveira, TC Araujo-Jorge, EM de Souza, GM de Oliveira, ... PLoS neglected tropical diseases 6 (6), e1696, 2012 | 69 | 2012 |
| Cellular Effects of Reversed Amidines on Trypanosoma cruzi CF Silva, MB Meuser, EM De Souza, MNL Meirelles, CE Stephens, P Som, ... Antimicrobial agents and chemotherapy 51 (11), 3803-3809, 2007 | 68 | 2007 |
| TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas’ heart disease RR Ferreira, R da Silva Abreu, G Vilar-Pereira, W Degrave, ... PLoS neglected tropical diseases 13 (7), e0007602, 2019 | 65 | 2019 |
| Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi EM De Souza, R Menna-Barreto, TC Araujo-Jorge, A Kumar, Q Hu, ... Parasitology 133 (1), 75-79, 2006 | 61 | 2006 |
| In Vitro and In Vivo Investigation of the Efficacy of Arylimidamide DB1831 and Its Mesylated Salt Form - DB1965 - against Trypanosoma cruzi Infection CF da Silva, DGJ Batista, GM Oliveira, EM de Souza, ER Hammer, ... PLoS One 7 (1), e30356, 2012 | 57 | 2012 |
| Aromatic guanyl hydrazones: Synthesis, structural studies and in vitro activity against Trypanosoma cruzi JC Messeder, LW Tinoco, JD Figueroa-Villar, EM Souza, R Santa Rita, ... Bioorganic & medicinal chemistry letters 5 (24), 3079-3084, 1995 | 57 | 1995 |
| Diamidine activity against trypanosomes: the state of the art MNC Soeiro, SL d Castro, EM De Souza, DGJ Batista, CF Silva, ... Current Molecular Pharmacology 1 (2), 151-161, 2008 | 54 | 2008 |
| In Vitro and In Vivo Activities of 1,3,4-Thiadiazole-2-Arylhydrazone Derivatives of Megazol against Trypanosoma cruzi K Salomão, EM De Souza, SA Carvalho, EF Da Silva, CAM Fraga, ... Antimicrobial agents and chemotherapy 54 (5), 2023-2031, 2010 | 52 | 2010 |
| Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies MNC Soeiro, AP Dantas, A Daliry, CF da Silva, DGJ Batista, EM de Souza, ... Memórias do Instituto Oswaldo Cruz 104, 301-310, 2009 | 51 | 2009 |
| Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies MNC Soeiro, AP Dantas, A Daliry, CF da Silva, DGJ Batista, EM de Souza, ... Memórias do Instituto Oswaldo Cruz 104, 301-310, 2009 | 51 | 2009 |
| Modulation induced by estradiol in the acute phase of Trypanosoma cruzi infection in mice EM de Souza, M Rivera, TC Araújo-Jorge, SL de Castro Parasitology Research 87, 513-520, 2001 | 50 | 2001 |
| Activities of Psilostachyin A and Cynaropicrin against Trypanosoma cruzi In Vitro and In Vivo CF da Silva, DGJ Batista, JS De Araújo, MM Batista, J Lionel, ... Antimicrobial agents and chemotherapy 57 (11), 5307-5314, 2013 | 42 | 2013 |
| Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo EM de Souza, GM Oliveira, DW Boykin, A Kumar, Q Hu, MDNC Soeiro Journal of Antimicrobial Chemotherapy 58 (3), 610-614, 2006 | 39 | 2006 |
